Synthetic approaches to novel analogues of DNA.
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Synthetic approaches to novel analogues of DNA.

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Published by University of Manchester in Manchester .
Written in English


Book details:

Edition Notes

Manchester thesis (Ph.D.), Department of Chemistry.

ContributionsUniversity of Manchester. Department of Chemistry.
The Physical Object
Pagination133p.
Number of Pages133
ID Numbers
Open LibraryOL16572781M

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"Compiles current tested and proven approaches to synthesize novel nucleoside analogues. Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical . Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical synthesis of common families of. Quinolones are broad-spectrum synthetic antibacterial drugs first obtained during the synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first became available for clinical consumption in and was used mainly for urinary tract infections caused by Escherichia coli and other pathogenic Gram-negative bacteria. Recently, significant work has been carried out to synthesize Cited by: A grand challenge that crosses synthetic chemistry and biology is the scalable production of functional analogues of biomacromolecules. We have focused our attention on the use of deoxynucleoside building blocks bearing non-natural bases to develop a synthetic methodology that allows for the construction of high molecular weight deoxynucleotide by:

In both approaches, synthetic chemistry plays a key role in generating high-quality small molecules collections. In fact, despite the vast success of the biological drugs (monoclonal antibodies or recombinant proteins), the favorable pharmacokinetic properties of small molecules libraries allowed them to remain as the gold standard for the development of new medications, especially in the case Author: Elena Lenci, Andrea Trabocchi. Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research. Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pentose sugar, either ribose or deoxyribose, and one of four analogue may have any of these altered. Synthetic biology (SynBio) is a multidisciplinary area of research that seeks to create new biological parts, devices, and systems, or to redesign systems that are already found in nature.. It is a branch of science that encompasses a broad range of methodologies from various disciplines, such as biotechnology, genetic engineering, molecular biology, molecular engineering, systems biology. Books shelved as dna: The Double Helix by James D. Watson, DNA: The Secret of Life by James D. Watson, The Family Tree Guide to DNA Testing and Genetic G.

Title:Synthesis and Biological Potentials of Quinoline Analogues: A Review of Literature VOLUME: 16 ISSUE: 7 Author(s):Leena Kumari, Salahuddin*, Avijit Mazumder, Daman Pandey, Mohammad Shahar Yar*, Rajnish Kumar, Rupa Mazumder, Mohammad Sarafroz, Mohamed Jawed Ahsan, Vivek Kumar and Sushma Gupta Affiliation:Noida Institute of Engineering and Technology (Pharmacy Institute), Plot No. Cited by: 2. Synthetic Biology -- A Primer gives a broad overview of the emerging field of synthetic biology and the foundational concepts on which it is built. It will be of interest to final year undergraduates, postgraduates and established researchers who are interested in learning about this exciting new field/5(5).   A standard DNA molecule. Floyd Romesberg and his team have expanded the genetic code from four letters to six by adding two new molecules they Author: Ian Sample. In Synthetic Biology, expert researchers in the field provide the latest developments in molecular biology techniques used in Synthetic ng on computational tools that will aid in systematising the design and construction of parts and systems. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics.